Disseminated intravascular coagulation is an acquired disorder, characterized by generalized and poorly controlled coagulation in the peripheral circulation with subsequent consumption coagulopathy. Due to its non-specific manifestations and often a fulminant course, it is considered a serious life-threatening condition with high mortality. In this algorithm, we look at some of the manifestations of this disorder and focus on the diagnosis and therapeutic interventions. Last but not least, we will introduce the use of viscoelastic methods in the diagnostics and optimization of transfusion and hemostatic therapy.
Disseminated intravascular coagulation (DIC) is a very insidious acquired syndrome, which is manifested by a complex breakdown of blood coagulation, with depletion of coagulation factors and platelets and subsequent thrombotization in various parts of the capillary bed. One of the intricacies of this syndrome is its slow-onset clinical and laboratory manifestations, which can escape our attention for a long time, and thus we can only notice DIC in the phase of massively accelerating manifestations, which dramatically worsen the condition of our patients, and the therapeutic intervention is no longer easy nor cheap. In general, it can be paraphrased that standing in front of a rolling avalanche always costs us dearly.
The goal of the interactive algorithm is to familiarize us with the clinical and laboratory manifestations of DIC on a casuistic model and to introduce the types of diseases that can cause this syndrome.
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