As is annually expected, we present you (from the position of media partner of the conference) with an online report from this year of The Colours of Sepsis. Our reporting team had the pleasure of attending the 25th-anniversary conference, which is one of the biggest conferences being held in the Czech Republic. Generally, the overall theme is regularly dedicated to Intensive Care and Emergency Medicine. The targeted audience is primarily doctors, nurses and other healthcare personnel in the field. However, dedicated medical students are welcomed as well.