Jan Máca, MD, PhD Deputy Head of the Department for science and education of Anaesthesiology, Resuscitation and Intensive Medicine, University Hospital Ostrava, Czech Republic
Sepsis is a serious life-threatening condition characterized by the presence of organ dysfunctions arising from the dysregulated host response to infection. The view of sepsis has evolved rapidly in recent decades. Mainly it is due to the increasing knowledge about its epidemiology, pathophysiology and therapy. As a result of population aging, increasing number of co-morbidities and improved diagnosis, the incidence of sepsis is increasing. Although sepsis is one of the most important topics and critical areas in intensive care, general and professional awareness remains inadequate. In 2016, a new definition of sepsis (sepsis-3) and a 5th revision of the Surviving Sepsis Campaign were recommended for intensive care patients with sepsis and septic shock. The presented algorithm is a necessary and clear knowhow to what to hold and what to think of a patient with sepsis. It highlights the need for rapid identification of the diagnosis and pathological agent and early initiation of supportive and causal treatment of sepsis.
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